Dr. Dennis Gross Skincare Advanced Retinol + Ferulic Overnight Wrinkle Treatment (30ml)

While you sleep, this serum gets to work.

The Advanced Retinol + Ferulic Overnight Wrinkle Serum Treatment is a dedicated PM formula that harnesses the skin's natural overnight renewal process to visibly reduce wrinkles, firm, and even tone - without the irritation that typically accompanies retinol use. The proprietary Phyto-Retinol Blend combines two forms of retinol with Bakuchiol, Rambutan, and Ferulic Acid to stimulate collagen production, accelerate cell turnover, and repair skin from the inside out. Niacinamide and Hyaluronic Acid ensure skin wakes up hydrated and strengthened, not dry and sensitized. Two to three pumps before bed. 

Noticeably smoother, firmer skin by morning - and measurably better results over time. 

Anyone dealing with fine lines, deeper wrinkles, loss of firmness, or uneven tone who wants a dedicated overnight treatment to do the heavy lifting while they sleep. Formulated for oily, normal, and combination skin types. Also a smart next step for anyone already using the Texture Renewal Serum in the AM who wants to build a complete retinol routine. 

• Reduces Fine Lines and Wrinkles - The Phyto-Retinol Blend combines two types of retinol with Bakuchiol, Rambutan, and Ferulic Acid to smooth fine lines and wrinkles overnight without irritation.
• Firms and Lifts - Retinol and Bakuchiol increase the thickness of the epidermis and dermis by stimulating collagen production in the papillary dermis for visibly firmer skin over time.
• Evens Tone and Texture - Retinol accelerates cell turnover to lift away dead skin cells and reveal smoother, younger-looking skin underneath.
• Deeply Hydrates Overnight - Niacinamide strengthens the moisture barrier while Hyaluronic Acid and Saccharide Isomerate maintain hydration levels throughout the night.
• Supports Natural Collagen - Retinol, Bakuchiol, and Rambutan directly stimulate collagen-producing fibroblasts in the upper dermis to build new collagen while protecting existing collagen from environmental damage.
• Non-Irritating Formula - Ferulic Acid counteracts the sensitizing effects of retinol, making this suitable for consistent nightly use without a prolonged adjustment period.
• Clinically Tested - In a 12-week clinical and consumer perception study, 91% saw smoother and more supple skin after just one week of use. 

• Retinol - A Vitamin A derivative that stimulates cell turnover, promotes collagen production, smooths texture, improves fine lines and wrinkles, controls oil production, and fades dark spots. Used here in two forms for enhanced efficacy and controlled delivery.
• Bakuchiol - A plant-derived retinol alternative from the babchi plant that delivers the same level of efficacy as retinol - improving fine lines, wrinkles, and loss of firmness - without redness or irritation, while reinforcing the skin's moisture barrier.
• Rambutan (Nephelium Lappaceum Leaf Extract) - A powerful antioxidant that protects natural collagen levels from environmental damage and visibly improves skin elasticity and radiance.
• Ferulic Acid - Counteracts the irritating effects of retinol, reduces the visible impact of sun damage, and enhances the stability and performance of other antioxidants in the formula.
• Niacinamide - Strengthens the skin's moisture barrier, controls excess oil, and helps even skin tone for a calmer, more balanced complexion over time.
• Hyaluronic Acid (Sodium Hyaluronate) - Draws moisture into the skin to maintain hydration levels throughout the night.
• Milk Thistle (Silybum Marianum Extract) - A potent antioxidant that helps protect skin from oxidative stress and supports overall skin health.
• Evening Primrose (Oenothera Biennis Flower Extract) - Rich in essential fatty acids that nourish and support the skin's moisture barrier.
• Vitamin E (Tocopherol) - An antioxidant that works synergistically with Ferulic Acid to protect skin from free radical damage and environmental stress.
• Green Tea (Camellia Sinensis Leaf Extract) - Provides antioxidant protection and helps reduce redness and oxidative stress during overnight repair.
• Adenosine - Supports the smoothing of fine lines and wrinkles and overall skin firmness. 

Use at night only. Apply 2-3 pumps to clean, dry skin. Massage into the face, then work down to the neck, décolletage, and shoulders. Follow with your PM moisturizer. Apply SPF the following morning.

Nighttime is when skin does its most significant repair work - cell turnover peaks, collagen synthesis accelerates, and skin is more receptive to active ingredients. This serum is built specifically to take advantage of that window. The Phyto-Retinol Blend is the same science behind the Texture Renewal Serum, but formulated here as a dedicated overnight treatment with a higher focus on wrinkle reduction and firming. If you want a complete retinol routine, pair the Texture Renewal Serum in the AM with this in the PM for a compounding effect on collagen support and skin renewal. The 91% smoother skin result after just one week makes the case clearly enough.