Dr. Dennis Gross Skincare DermInfusions Fill + Repair Serum (30ml)

Four sizes of Hyaluronic Acid. Four peptides. One serum that works at every level of the skin.

The DermInfusions™ Fill + Repair Serum is a fast-acting, needle-free alternative to injectables that works three-dimensionally to fill fine lines, restore volume, firm sagging skin, and deeply hydrate - all without a dermatologist appointment. Four molecular sizes of Hyaluronic Acid penetrate at different depths to create a genuine plumping effect from within, while a volumizing complex of four peptides visibly firms and lifts. Niacinamide and Ectoin strengthen the moisture barrier, and a supporting cast of Ceramides, Bakuchiol, Squalane, and botanical extracts work together to repair, soothe, and protect.

The result is skin that looks fuller, firmer, and more hydrated - immediately and over time.

Who's It For

Anyone dealing with visible fine lines, loss of firmness, sagging, or persistent dryness. Formulated for oily, normal, and combination skin types, and designed for consistent AM/PM use as part of a complete anti-aging routine.

Key Benefits

• Visibly Fills Fine Lines - Clinically proven to immediately improve the appearance of fine lines, sagging, loss of firmness, and elasticity from first use.
• Deep, Multi-Level Hydration - Four sizes of Hyaluronic Acid molecules penetrate at different depths to visibly plump, restore bounce, and hydrate skin three-dimensionally.
• Firms and Lifts - A volumizing complex of four peptides works together to visibly firm and lift the appearance of sagging skin over time.
• Strengthens the Moisture Barrier - Niacinamide and Ectoin reinforce skin's natural barrier to reduce moisture loss and improve overall skin resilience.
• Controls Redness - Calming ingredients including Bisabolol, Chamomile, and Colloidal Oatmeal soothe and minimize visible redness.
• Repairs and Protects - Ceramides, Sphingolipids, and Phospholipids restore the skin's lipid barrier while antioxidants including Glutathione, Superoxide Dismutase, and Kakadu Plum defend against environmental damage.
• Clinically Tested - In a four-week clinical and consumer perception study on 34 subjects, 94% showed immediate skin barrier improvement at four weeks, 100% showed skin barrier improvement at two weeks, and 91% saw firmer skin and felt skin was plumped and hydrated. 

Key Ingredients

• Hyaluronic Acid Complex (Sodium Hyaluronate, Hydrolyzed Sodium Hyaluronate, Sodium Acetylated Hyaluronate, Sodium Hyaluronate Crosspolymer) - Four molecular sizes of Hyaluronic Acid that penetrate at different depths to create a three-dimensional plumping and filling effect throughout the skin.
• Peptide Complex (Acetyl Hexapeptide-8, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Oligopeptide-2) - Four peptides that work together to visibly add volume, firm skin, and support the skin's structural proteins over time.
• Niacinamide - Strengthens the skin's moisture barrier, controls excess oil, minimizes the appearance of pores, and helps even skin tone.
• Ectoin - A powerful barrier-strengthening ingredient that protects skin from environmental stressors and helps maintain healthy moisture levels. 
• Ceramide Complex (Ceramide NP, Ceramide AP, Ceramide EOP) - Restores the skin's lipid barrier to lock in moisture and protect against irritation and moisture loss.
• Bakuchiol - A plant-derived retinol alternative that supports collagen production and improves skin firmness without irritation. 
• Squalane - A lightweight emollient that prevents moisture loss and keeps skin soft and supple without clogging pores.
• Kakadu Plum (Terminalia Ferdinandiana Fruit Extract) - One of the world's richest natural sources of Vitamin C, providing powerful antioxidant protection and brightening benefits.
• Ashwagandha (Withania Somnifera Root Extract) - An adaptogenic herb that helps protect skin from stress-related aging and supports overall skin resilience.
• Chaga Mushroom (Inonotus Obliquus Extract) - A potent antioxidant that protects against free radical damage and supports overall skin health.
• Colloidal Oatmeal - Soothes and calms sensitive or reactive skin while providing gentle moisture support.
• Caffeine - Helps de-puff and reduce the appearance of redness and inflammation in skin. 
• Bisabolol - Soothes and calms skin with gentle anti-inflammatory properties.
• Green Tea (Camellia Sinensis Leaf Extract) - Delivers antioxidant protection and helps reduce redness and oxidative stress. 

How To Use

Use morning and night. Using 2-3 pumps, massage into the full face. Work down to the neck and décolletage. Focus additional product on areas where fine lines and wrinkles are most visible. Follow with your preferred moisturizer. 

Why MASC Recommends This

The multi-size Hyaluronic Acid approach is what sets this serum apart from standard hydration products. Most serums use a single molecular weight of Hyaluronic Acid, which means they can only work at one depth. Using four sizes means this serum is genuinely working at every level - surface plumping, mid-depth hydration, and deeper structural support - simultaneously. Add four peptides, a full ceramide complex, and some of the most potent antioxidants in skincare, and you have a serum that earns the "injectable alternative" positioning. The clinical results at two and four weeks are strong, and the ingredient list backs up every claim on the label.